Breast Cancer

What is FISH ?

Fluorescence in situ hybridization (FISH) is an in situ hybridization technique that uses fluorescence signals to detect probes. It combines the high sensitivity, safety and intuitiveness of fluorescence signal with the high specificity of in situ hybridization. The fluorescent labeled nucleic acid probe is used for in situ hybridization with the nucleic acid of the tested sample. The fluorescence signals can be identified and counted under a fluorescence microscope, so as to detect and diagnose cells and tissue samples with chromosomal or genetic abnormalities, and provide accurate basis for the classification, prognostication and prognosis of various gene-related diseases. Automated FISH diagnostic systems have been approved by the US FDA under the medical device stream, a mark of the maturity and reliability of the technique.

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