Human CYP2C19 Gene Detection Kit
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CYP2C19 Gene Detection Kit is a PCR-based in vitro diagnostic test designed to detect polymorphism of CYP2C19 gene CYP2C19*2, CYP2C19*3 and CYP2C19*17 in whole blood samples. The detection of CYP2C19 genotype can determine the type of metabolic rate of patients and adjust the dosage reasonably, which is an effective way to improve the cure rate of related diseases and reduce toxic side effects.
Corresponding Drugs: Clopidogrel, Omeprazole, Diazepam, Phenytoin sodium, etc.
| Easy Operation
·Unique fluorescence PCR technology ·Each sample occupies only one reaction well ·90 mins to complete |
Simple Results Analysis
·Simplified analysis without △CT value reading ·Simple training |
Comprehensive Detection
·Detect *17 site beside *2 and *3 sites Cover all metabolic types including ultra-fast metabolic types. |
Product Information
| Cat.No. | Product Name | Technology | Specification | Supply Format |
| YZYMT-006 | Human CYP2C9 & VKORC1 Gene Detection Kit | PCR-Fluorescence Method | 20 tests/ kit | CE-IVD/RUO |
The CYP2C19 gene is involved in the metabolism of many important drugs for clinical applications, such as clopidogrel, omeprazole and phenobarbital. The genetic polymorphism of this gene leads to differences in the metabolic capacity of the relevant drugs in different populations,which may cause adverse reactions or poor efficacy of patients.
Clinical Significance (Clopidogre)
| Gene Polymorphism | Base Change | Mutation Frequency | Medication Guidance |
| CYP2C19*2 | CCG>CCA | 30%-35% | Mutations require increased clopidogrel dosing |
| CYP2C19*3 | TGG>TGA | 5%-10% | |
| CYP2C19*17 | CAT>TAT | 1%-2% | Mutations require reduced clopidogrel dosing |
