Human MTHFR Gene Detection Kit
MTHFR Gene Detection Kit is a PCR-based in vitro diagnostic test designed to detect polymorphism of MTHFR 677C>T in genomic DNA extracted from venous whole blood samples. The detection results of this product only represent the detection results for human MTHFR gene, which provides a reference for clinicians to individualized medication.
Easy Operation
·Unique fluorescence PCR technology ·Each sample occupies only one reaction well ·90 mins to complete |
Simple Results Analysis
·Simplified analysis without △CT value reading ·Simple training |
Reliable Quality
·With thorough clinical validation, 100% compliance with Sanger sequencing |
Product Information
Cat.No. | Product Name | Technology | Specification | Supply Format |
YZYMT-014 | Human MTHFR Gene Detection Kit | PCR-Fluorescence Method | 20 tests/ kit | CE-IVD/RUO |
Clinical Significance ( Allopurinol)
The deficiency of folate metabolism can cause many diseases, including neonatal birth defects, pregnancy induced hypertension and H-type hypertension. The abnormality of enzyme activity caused by MTHFR(5,10-methylenetetrahydrofolic acid reductase)gene mutation is the main cause of folate metabolismdisorder. MTHFR gene detection can predict the folate metabolism ability of individuals and assist clinicians to develop personalized folate supplementation program.
This kit can indicate the risk of cardiovascular and cerebrovascular diseases in hypertensive population for patients with H-type hypertension, people with a family history of strok or hypertensive patients with risk factors such as hyperlipidemia.
The polymorphism of MTHFR Gene in This Kit
Gene | Polymorphism | Base | Fluorescent Channel |
MTHFR | 677C | GCC | FAM |
677T | GTC | VIC |